at the University of California, Berkeley
There are three core laboratories on campus that offer expertise, instruction, and instrumentation in optical microscopy for research.
The CNR Biological Imaging Facility (This lab): Confocal, deconvolution, and widefield fluorescence microscopy, live-cell imaging, microtechnique, training in digital image processing and analysis. Located in 381 Koshland Hall
Molecular Imaging Center: Multi-photon laser scanning confocal microscopy, electrophysiology, live-cell imaging. Located in LSA and LKS.
The Golub Microscope Collection: Web site dedicated to Dr. Orville J. Golub's collection of antique microscopes from the 17th–20th Centuries. The collection is located in VLSB
The Biological Imaging Facility is a core microscope imaging lab at the University of California, Berkeley.
The BIF specializes in Live-Cell Widefield, Confocal (including FCS),
Spinning Disk, and Super-Resolution fluorescence microscopy
(SIM, PALM, TIRF).
After June 21 we no longer have a Density Budget or 6' social distancing rule, and because of this we will allow self-reservations and in-person training.
If you wish to be trained, please complete this Google Form, then contact Denise. Once you have completed this training Form and are trained, you will be authorized to reserve instrument time and enter the BIF.
If you are already trained feel free to reserve instrument time yourself. Contact us for the Calendar signup credentials.
Please visit the Vice Chancellor for Research website for guidance on Planning for Research Continuity
These cells are C. elegans germline showing late pachytene nuclei. C. elegans germline forms a syncytium; a structure with no cytosol, with the nuclei organized in a free-nuclear state inside the gonad. During meiosis, there is conserved association between chromosomes and the nuclear envelope (NE) and that is known to be mediated by a pair of SUN-domain and KASH-domain protein in the NE. The preparation was stained with DAPI, a KASH domain protein ZYG-12 (Red), and a newly characterized protein named MJL-1 (Green). This image was acquired on the Zeiss Elyra SIM microscope in the BIF.