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Microscopy Facilities
at the University of California, Berkeley

There are three core laboratories on campus that offer expertise, instruction, and instrumentation in optical microscopy for research.

These are the images of the distal metaphysis of mice femur bone in longitudinal section stained with Hematoxylin & Eosin using the Zeiss AxioImager M2 Microscope in the BIF. The bones were fixed in Bouin's, decalcified, dehydrated, infiltrated, and embedded in paraffin wax and then sectioned at 10Ķm using the Leica RM2255 Motorized Microtome. These images were acquired using the 5x objective lens and a QImaging MicroPublisher Color camera. These images demonstrate the importance of a particular gene in the Vitamin A metabolic pathway. What these images show is that mutant mice (R) have higher number of adipocytes (arrows) in the bone marrow of distal femur compared to the wildtype mice (L).

Image contributed by Myeongcheol (Mitch) Kim of Napoli Lab.

The Biological Imaging Facility is a core microscope imaging lab at the University of California, Berkeley.
The BIF specializes in Widefield, Confocal, Deconvolution and Super-Resolution fluorescence microscopy (SIM, PALM, TIRF).

Past IOMs
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Fri, Apr 1, 2016