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Microscopy Facilities
at the University of California, Berkeley

There are three core laboratories on campus that offer expertise, instruction, and instrumentation in optical microscopy for research.

The Biological Imaging Facility is a core microscope imaging lab at the University of California, Berkeley.
The BIF specializes in Widefield, Confocal, Deconvolution, Spinning Disk, and Super-Resolution fluorescence microscopy
(SIM, PALM, TIRF).

Past IOMs
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Call-era all your friends! Everyone is toxin about the amazing filamenting bacteria!

Toxin/anti-toxin systems were initially a mysterious genetic feature of bacterial plasmids and chromosomes. They are now known to play important roles in plasmid inheritance, stability of mobile chromosomal regions and the formation of "persister" cells. Induction of a chromosomally-encoded toxin without its anti-toxin makes bacterial cells filament into bizarre shapes. The target of this toxin is still unknown, but as can be seen in image B the cells certainly are not dividing normally. Shown here are the first (A) and last (B) image of a 6h post-induction time lapse experiment performed on the AxioObserver Z1/CellASIC microfluidics system in the BIF.

Image contributed by Kristen LeGault of the Seed lab, PMB.

Tue, Jan 31, 2017