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Microscopy Facilities
at the University of California, Berkeley

There are three core laboratories on campus that offer expertise, instruction, and instrumentation in optical microscopy for research.

The Biological Imaging Facility is a core microscope imaging lab at the University of California, Berkeley.
The BIF specializes in Widefield, Confocal, Deconvolution, Spinning Disk, and Super-Resolution fluorescence microscopy

Past IOMs


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The ParB protein binds to sequences adjacent to the origin of replication; therefore, a fluorescent fusion to this protein makes it possible to follow the dynamics of the bacterial chromosome during the cell cycle. In short cells (early in the cell cycle), the Agrobacterium tumefaciens ParB (fused to mCherry) is visible as a distinct focus at the old cell pole. As cells grow, two foci are visible indicating the chromosome has been replicated. One of the foci migrates across the cell to the other pole to ensure that each sibling cell has a copy of the chromosome. This image was taken on the Zeiss AxioObserver. Z1 in the BIF.

Image contributed by Jose Sebastian Robalino Espinosa and John Zupan from the Zambryski Lab.

Sun, Dec 2, 2018